{ "_id": "6a2134d6cd65a98ecbd2649e", "Package": "CompAREdesign", "Title": "Statistical Functions for the Design of Studies with Composite\nEndpoints", "Version": "2.4.0", "Author": "Marta Bofill Roig [aut, cre], Jordi Cortes Martinez [aut],\nGuadalupe Gomez Melis [ctb]", "Authors@R": "c(person(given = \"Marta\",\nfamily = \"Bofill Roig\",\nrole = c(\"aut\", \"cre\"),\nemail = \"marta.bofill.roig@upc.edu\"),\nperson(given = \"Jordi\",\nfamily = \"Cortes Martinez\",\nrole = \"aut\"),\nperson(given = \"Guadalupe\",\nfamily = \"Gomez Melis\",\nrole = \"ctb\"))", "Maintainer": "Marta Bofill Roig ", "Description": "It has been designed to calculate the required sample size\nin randomized clinical trials with composite endpoints. It also\ncalculates the expected effect and the probability of observing\nthe composite endpoint, among others. The methodology can be\nfound in Bofill & Gómez (2019) and Gómez\n& Lagakos (2013) .", "URL": "https://compare-composite.github.io/compare/", "License": "GPL-3", "Encoding": "UTF-8", "VignetteBuilder": "knitr", "RoxygenNote": "7.3.2", "NeedsCompilation": "no", "Packaged": { "Date": "2026-06-04 08:14:31 UTC", "User": "root" }, "Config/pak/sysreqs": "cmake make libgsl0-dev libicu-dev", "Repository": "https://martabofillroig.r-universe.dev", "Date/Publication": "2025-03-05 03:40:02 UTC", "RemoteUrl": "https://github.com/cran/CompAREdesign", "RemoteRef": "HEAD", "RemoteSha": "209fdfef64a291737429e26f7734b77858520902", "MD5sum": "1211be757edfb8f0fa8b3a9b7661df71", "_user": "martabofillroig", "_type": "src", "_file": "CompAREdesign_2.4.0.tar.gz", "_fileid": "6ff86bf3505a64b559fdbe766939f8f00543d0f7622ab6cab8600dc546bb0d1f", "_filesize": 623728, "_sha256": "6ff86bf3505a64b559fdbe766939f8f00543d0f7622ab6cab8600dc546bb0d1f", "_created": "2026-06-04T08:14:31.000Z", "_published": "2026-06-04T08:18:30.703Z", "_distro": "noble", "_jobs": [ { "job": 79477627514, "time": 193, "config": "linux-devel-x86_64", "r": "4.7.0", "check": "OK", "artifact": "7406430152" }, { "job": 79477627539, "time": 176, "config": "linux-release-x86_64", "r": "4.6.0", "check": "OK", "artifact": "7406424596" }, { "job": 79477627528, "time": 97, "config": "macos-oldrel-arm64", "r": "4.5.3", "check": "OK", "artifact": "7406399240" }, { "job": 79477627569, "time": 185, "config": "macos-release-arm64", "r": "4.6.0", "check": "OK", "artifact": "7406427331" }, { "job": 79477041530, "time": 222, "config": "source", "r": "4.6.0", "check": "OK", "artifact": "7406367526" }, { "job": 79477627541, "time": 139, "config": "wasm-release", "r": "4.6.0", "check": "OK", "artifact": "7406413191" }, { "job": 79477627599, "time": 193, "config": "windows-devel", "r": "4.7.0", "check": "OK", "artifact": "7406430008" }, { "job": 79477627625, "time": 128, "config": "windows-oldrel", "r": "4.5.3", "check": "OK", "artifact": "7406409210" }, { "job": 79477627673, "time": 147, "config": "windows-release", "r": "4.6.0", "check": "OK", "artifact": "7406415973" } ], "_buildurl": "https://github.com/r-universe/martabofillroig/actions/runs/26939434770", "_status": "success", "_host": "GitHub-Actions", "_upstream": "https://github.com/cran/CompAREdesign", "_commit": { "id": "209fdfef64a291737429e26f7734b77858520902", "author": "Marta Bofill Roig ", "committer": "cran-robot ", "message": "version 2.4.0\n", "time": 1741146002 }, "_maintainer": { "name": "Marta Bofill Roig", "email": "marta.bofill.roig@upc.edu", "login": "martabofillroig", "description": "Serra Húnter Fellow at the Universitat Politècnica de Catalunya - BarcelonaTech\n\nClinical Trials | Survival Analysis", "uuid": 26740298 }, "_registered": true, "_dependencies": [ { "package": "stats", "role": "Imports" }, { "package": "utils", "role": "Imports" }, { "package": "copula", "role": "Imports" }, { "package": "ggplot2", "role": "Imports" }, { "package": "ggpubr", "role": "Imports" }, { "package": "rootSolve", "role": "Imports" }, { "package": "numDeriv", "role": "Imports" }, { "package": "knitr", "role": "Suggests" }, { "package": "rmarkdown", "role": "Suggests" } ], "_owner": "cran", "_selfowned": true, "_usedby": 1, "_updates": [], "_tags": [], "_stars": 0, "_contributors": [ { "user": "martabofillroig", "count": 9, "uuid": 26740298 } ], "_userbio": { "uuid": 26740298, "type": "user", "name": "Marta Bofill Roig", "description": "Serra Húnter Fellow at the Universitat Politècnica de Catalunya - BarcelonaTech\r\n\r\nClinical Trials | Survival Analysis" }, "_downloads": { "count": 201, "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/CompAREdesign" }, "_devurl": "https://github.com/compare-composite/compare", "_searchresults": 2, "_rbuild": "4.6.0", "_assets": [ "extra/citation.cff", "extra/citation.html", "extra/citation.json", "extra/citation.txt", "extra/CompAREdesign.html", "extra/contents.json", "manual.pdf" ], "_realowner": "martabofillroig", "_cranurl": false, "_releases": [ { "version": "1.5", "date": "2020-12-09" }, { "version": "1.6", "date": "2021-01-11" }, { "version": "1.7", "date": "2021-02-02" }, { "version": "1.9", "date": "2021-06-15" }, { "version": "2.0", "date": "2022-09-17" }, { "version": "2.1", "date": "2022-09-29" }, { "version": "2.2", "date": "2022-10-02" }, { "version": "2.3.1", "date": "2024-02-15" }, { "version": "2.4.0", "date": "2025-03-05" } ], "_exports": [ "ARE_cbe", "ARE_tte", "CopulaSelection", "dClayton", "dFGM", "dFrank", "dGumbel", "dNormal", "effectsize_cbe", "effectsize_tte", "f_sim", "freedman_formula", "get_prob1", "lower_corr", "MarginalsSelection", "plot_tte", "prob_cbe", "samplesize_cbe", "samplesize_tte", "schoenfeld_formula", "simula_cbe", "simula_tte", "Sstar", "Sstar_func_perc", "surv_tte", "upper_corr" ], "_help": [ { "page": "ARE_cbe", "title": "ARE method for composite binary endpoints", "topics": [ "ARE_cbe" ] }, { "page": "ARE_tte", "title": "ARE method for composite time to event endpoints", "topics": [ "ARE_tte" ] }, { "page": "effectsize_cbe", "title": "Effect for composite binary endpoints", "topics": [ "effectsize_cbe" ] }, { "page": "effectsize_tte", "title": "Effect for composite time-to-event endpoints", "topics": [ "effectsize_tte" ] }, { "page": "lower_corr", "title": "Lower bound for Pearson's Correlation", "topics": [ "lower_corr" ] }, { "page": "plot_tte", "title": "Plot graphics related to the composite endpoint.", "topics": [ "plot_tte" ] }, { "page": "prob_cbe", "title": "Probability of composite binary endpoints", "topics": [ "prob_cbe" ] }, { "page": "samplesize_cbe", "title": "Sample size for composite binary endpoints", "topics": [ "samplesize_cbe" ] }, { "page": "samplesize_tte", "title": "Sample size for composite time to event endpoints", "topics": [ "samplesize_tte" ] }, { "page": "simula_cbe", "title": "Simulation of binary composite endpoints", "topics": [ "simula_cbe" ] }, { "page": "simula_tte", "title": "Simulation of composite time-to-event endpoints", "topics": [ "simula_tte" ] }, { "page": "surv_tte", "title": "Survival function for composite time-to-event endpoints", "topics": [ "surv_tte" ] }, { "page": "upper_corr", "title": "Upper bound for Pearson's Correlation", "topics": [ "upper_corr" ] } ], "_pkglogo": "https://github.com/cran/CompAREdesign/raw/HEAD/man/figures/logo.png", "_rundeps": [ "abind", "ADGofTest", "backports", "boot", "broom", "car", "carData", "cli", "cluster", "colorspace", "copula", "corrplot", "cowplot", "cpp11", "Deriv", "doBy", "dplyr", "farver", "forecast", "Formula", "fracdiff", "generics", "ggplot2", "ggpubr", "ggrepel", "ggsci", "ggsignif", "glue", "gridExtra", "gsl", "gtable", "isoband", "labeling", "lattice", "lifecycle", "lme4", "lmtest", "magrittr", "MASS", "Matrix", "MatrixModels", "mgcv", "microbenchmark", "minqa", "modelr", "mvtnorm", "nlme", "nloptr", "nnet", "numDeriv", "pbkrtest", "pcaPP", "pillar", "pkgconfig", "polynom", "pspline", "purrr", "quantreg", "R6", "rbibutils", "RColorBrewer", "Rcpp", "RcppArmadillo", "RcppEigen", "Rdpack", "reformulas", "rlang", "rootSolve", "rstatix", "S7", "scales", "SparseM", "stabledist", "stringi", "stringr", "survival", "tibble", "tidyr", "tidyselect", "timeDate", "urca", "utf8", "vctrs", "viridisLite", "withr", "zoo" ], "_vignettes": [ { "source": "binary_endpoints.Rmd", "filename": "binary_endpoints.html", "title": "CompAREdesign: Binary endpoints", "author": "Marta Bofill Roig, Jordi Cortés Martínez and Guadalupe Gómez Melis", "engine": "knitr::rmarkdown", "headings": [ "Binary endpoint: TUXEDO TRIAL", "Input Parameters", "ARE: Asymptotic Relatively Efficiency", "Effect size of the Composite Endpoint", "Sample size", "References" ], "created": "2025-03-05 03:40:02", "modified": "2025-03-05 03:40:02", "commits": 1 }, { "source": "simulations.Rmd", "filename": "simulations.html", "title": "CompAREdesign: Simulations", "author": "Jordi Cortés Martínez, Marta Bofill Roig and Guadalupe Gómez Melis", "engine": "knitr::rmarkdown", "headings": [ "Simulations", "Simulation of composite time-to-event endpoints" ], "created": "2025-03-05 03:40:02", "modified": "2025-03-05 03:40:02", "commits": 1 }, { "source": "time_to_event_endpoints.Rmd", "filename": "time_to_event_endpoints.html", "title": "CompAREdesign: Time-to-event endpoints", "author": "Jordi Cortés Martínez, Marta Bofill Roig and Guadalupe Gómez Melis", "engine": "knitr::rmarkdown", "headings": [ "Case study: ZODIAC Trial", "Input Parameters", "ARE: Asymptotic Relatively Efficiency", "Effect size of the Composite Endpoint", "Sample size", "Influence of hazards rates over time on the effect size", "Summary plots", "References" ], "created": "2025-03-05 03:40:02", "modified": "2025-03-05 03:40:02", "commits": 1 } ], "_score": 2.9542425094393248, "_indexed": true, "_nocasepkg": "comparedesign", "_universes": [ "martabofillroig", "compare-composite" ], "_binaries": [ { "r": "4.7.0", "os": "linux", "version": "2.4.0", "date": "2026-06-04T08:17:15.000Z", "distro": "noble", "commit": "209fdfef64a291737429e26f7734b77858520902", "fileid": "73d187654c9980b1f763f2cb8d7b3e3eb9096d48ab96c5527e530d89fb9cc1df", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/martabofillroig/actions/runs/26939434770" }, { "r": "4.6.0", "os": "linux", "version": "2.4.0", "date": "2026-06-04T08:17:04.000Z", "distro": "noble", "commit": "209fdfef64a291737429e26f7734b77858520902", "fileid": "e3d33236fe76db6c48ee14ed16c7a6e7af864190e0317c914a02682d625a1a6d", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/martabofillroig/actions/runs/26939434770" }, { "r": "4.5.3", "os": "mac", "version": "2.4.0", "date": "2026-06-04T08:16:03.000Z", "commit": "209fdfef64a291737429e26f7734b77858520902", "fileid": "7c384073ea6653a165e89d9363b86ec63ee09262e3d4285b31299b51e6bab6f1", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/martabofillroig/actions/runs/26939434770" }, { "r": "4.6.0", "os": "mac", "version": "2.4.0", "date": "2026-06-04T08:16:57.000Z", "commit": "209fdfef64a291737429e26f7734b77858520902", "fileid": "cd92a3364a08f12cfc905fc662ad2f255deeec2816336d48244c0537dabf642f", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/martabofillroig/actions/runs/26939434770" }, { "r": "4.6.0", "os": "wasm", "version": "2.4.0", "date": "2026-06-04T08:17:13.000Z", "commit": "209fdfef64a291737429e26f7734b77858520902", "fileid": "1fe750cbb7af317e9b420704b2f85bd1b71b7c64efb967027b2b1436eab63334", "status": "success", "buildurl": "https://github.com/r-universe/martabofillroig/actions/runs/26939434770" }, { "r": "4.7.0", "os": "win", "version": "2.4.0", "date": "2026-06-04T08:17:10.000Z", "commit": "209fdfef64a291737429e26f7734b77858520902", "fileid": "dfafb68394e41e73c7ec8436c15533420ae05c0c98a247164a5fd9a622881e73", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/martabofillroig/actions/runs/26939434770" }, { "r": "4.5.3", "os": "win", "version": "2.4.0", "date": "2026-06-04T08:15:59.000Z", "commit": "209fdfef64a291737429e26f7734b77858520902", "fileid": "a0197b9f81e19125182efc3c1c934c4382dca7f39df53e64d725bb2cd3956674", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/martabofillroig/actions/runs/26939434770" }, { "r": "4.6.0", "os": "win", "version": "2.4.0", "date": "2026-06-04T08:16:22.000Z", "commit": "209fdfef64a291737429e26f7734b77858520902", "fileid": "11ce9366ed683da177b7b2095dcce9ff623704915eecfce3ef0c8c270d7e02bc", "status": "success", "check": "OK", "buildurl": "https://github.com/r-universe/martabofillroig/actions/runs/26939434770" } ] }